Parasiticide



Patented Nov. 12, 1940 UNITED STATES PATENT OFFICE PARASITICIDE poration of New Jersey No Drawing. Application October 14, 1931!,

. Serial No. 234,957

1 Claim This invention relates to improvements in parasiticidal preparations such as fungicides, fumigants, insecticides, etc.

More particularly the invention relates to a 5 parasiticidal preparation containing as an active constituent a 2,5-dialkyl pyrrolyl compound.

A preferred compound is 2,5-dimethyl-pyrrole having the formula This chemical can be readily made in known manner from acetonyl-acetone and ammonia,

and possesses marked toxicity towards living organisms that are injurious to man. Its toxic properties are shown in the results of the following tests:

1. A solution was made up consisting of 10% 2,5-dimethyl-pyrro1e, 1% Emulphor EL, 2. commercial emulsifying agent, and 89% white oil. An emulsion was made comprising 1 part of the above described 10% solution of 2,5-dimethylpyrrole and 100 parts of water. Leaves of Golden Gleam nasturtium on which were placed 409 black bean aphids (Aphis rumicz's) were thoroughly sprayed with this emulsion at a pressure of 17 lbs.

At the end of 24 hrs., 389 aphids had died, which is equivalent to a 95.1% mortality, whereas in a control experiment in which 580 aphids were used, only 11 had died at the end of 24 hrs., which is equivalent to a 1.8% mortality.

2. 2,5-dimethy1-pyrrole is also an excellent fumigant. Black carpet beetle larvae (Attagenus pzceus) were placed in a jar and 2,5-dimethylpyrrole was applied as a mist. The tabulation that is given below shows the efl'ectiveness of this fumigant in low concentrations. 5

Percent Concentration of 2.5dimethyl-pyrrole dead,

. 15 3. 2,5-dimethyl-pyrrole shows marked toxicity to the fungus Macrosporium sarcinaeforme in concentrations of 5 grams per liter of water, or less, preferably in the presence of a wetting agent such as sulphite lye, Goulac or others. In many 20 instances the spore germination was reduced to 0%.

4. 2.5-dimethyl-pyrrole is toxic towards Colorado potato beetle larvae. Irish potato leaves were dipped in a 10% water emulsion of 2,5-di- 26 methyl-pyrrole and allowed to drain. Colorado potato beetle larvae were placed upon the leaves.

All larvae were dead in mins, whereas there was no mortality in a control run,

Having thus described my invention, what I 30 claim and desire to protect by Letters Patent is:

A parasiticide preparation containing as an active constituent, 2,5-dimethyl pyrrole.

WILLIAM P. TER HORST. 

